To evaluate the safety and efficacy of Levobetaxolol in Chinese patients with glaucoma.
To evaluate the safety and efficacy of Levobetaxolol in Chinese patients with primary open-angle glaucoma or ocular hypertension.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
366
one drop per time; twice daily
one drop per time; twice daily
Zhongshan ophthalmic center, Sun Yat-sen University
Guangzhou, Guangdong, China
Change in intraocular pressure (IOP) from baseline at week 8 after the treatment (a.m.)
Change in intraocular pressure (IOP) from baseline at week 8 after the treatment (a.m.)
Time frame: 8 weeks
Change in intraocular pressure (IOP) from baseline to week 2
Change in intraocular pressure (IOP) from baseline to week 2
Time frame: 2 weeks
Change in intraocular pressure (IOP) from baseline to week 4
Change in intraocular pressure (IOP) from baseline to week 4
Time frame: 4 weeks
Change in intraocular pressure (IOP) from baseline to week 8 (p.m.)
Change in intraocular pressure (IOP) from baseline to week 8 (p.m.)
Time frame: 8 weeks
Change from baseline in mean visual field defect (MD) at 8 weeks after the treatment
Change from baseline in mean visual field defect (MD) at 8 weeks after the treatment
Time frame: 8 weeks
Change in visual field pattern standard deviation (PSD) from baseline at 8 weeks after the treatment
Change in visual field pattern standard deviation (PSD) from baseline at 8 weeks after the treatment
Time frame: 8 weeks
Change in retinal nerve fiber layer (RNFL) thickness from baseline at 8 weeks after the treatment
Change in retinal nerve fiber layer (RNFL) thickness from baseline at 8 weeks after the treatment
Time frame: 8 weeks
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Change in visual acuity test at week 2
Change in visual acuity test at week 2
Time frame: 2 weeks
Change in visual acuity test at week 4
Change in visual acuity test at week 4
Time frame: 4 weeks
Change in visual acuity test at week 8
Change in visual acuity test at week 8
Time frame: 8 weeks