Changes of Tear-film Lipid Layer Thickness and Ocular Aberration After Treatment of Meibomian Gland Dysfunction

Yonsei University45 enrolled

Overview

In this study, investigator aim to evaluate the changes of tear-film lipid layer thickness and ocular aberration after treatment of meibomian gland dysfunction. In case of stage 3 or 4 meibomian gland dysfunction, participants will be treated using conventional treatment modalities. Before treatment and after 1 and 2 months of treatment, a variety of ophthalmic examination, tear-film lipid layer thickness, and ocular aberration are going to measured and compared.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Meibomian Gland Dysfunction

Interventions

Treatment of Meibomian gland dysfunctionDRUG

artificial tears, 3% Diquafosol Tetrasodium eye drops, steroid eye drops, squeezing of meibomian glands, cleansing of eyelids.

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1\. age over 19 years old, with moderate to severe Meibomian gland dysfunction. Exclusion Criteria: 1. patients with history of previous ocular or intraocular surgery 2. ocular infection, non dry eye ocular inflammation, ocular allergy, autoimmune disease 3. history of intolerance or hypersensitivity to any component of the study medications 4. wearing contact lenses during the study period, presence of current punctal occlusion 5. pregnancy, lactating women, and children

Locations (1)

Department of Ophthalmology, Yonsei Univeristy College of Medicine

Seoul, South Korea