The objective of this study is to evaluate sennosides as an adjunct to sodium picosulfate magnesium citrate (Pico Salax) in preparation for colonoscopy. We will compare different doses and administration times. The primary outcome is number of bowel motions produced. Secondary outcomes include the quality of bowel cleansing and patient tolerability.
We will compare different doses and administration times in patients booked for morning colonoscopy. The primary outcome is number of bowel motions produced in total by the sennosides. Secondary outcomes include the quality of bowel cleansing and patient tolerability.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
100
Each group will be assigned different doses of sennosides and varying times of administration
Hotel Dieu Hospital
Kingston, Ontario, Canada
Hotel Dieu Hospital
Kingston, Ontario, Canada
Bowel movements, as measured by patient diary
The primary outcome of this pilot study is the number of bowel movements. Patients will record the timing and number of bowel motions produced.
Time frame: 2 days
Colon cleansing, as measured by The Ottawa Scale and Aronchick Bowel Cleansing Scale
The secondary outcome is colon cleansing efficacy. The endoscopist will grade the cleansing quality of the colon using two standardized measures - the Ottawa Scale and the 5-point Aronchick Bowel Preparation Scale
Time frame: 2 days
Tolerability, as measured by patient questionnaire
The secondary outcome is patient tolerability. Patients will be asked to complete a questionnaire examining symptoms such as nausea, bloating, vomiting, and abdominal pain.
Time frame: 2 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.