Effect of Caudal Nalbuphine on Postoperative Analgesia in Children

Assiut University60 enrolled

Overview

Nalbuphine as an adjuvant to bupivacaine caudal anesthesia for postoperative analgesia in children undergoing Hypospadias repair. 2 groups, 30 patients each

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Postoperative Pain

Interventions

Nalbuphine plus BupivacaineDRUG

Addition of caudal Nalbuphine to the standard Bupivacaine

BupivacaineDRUG

Caudal Bupivacaine is the standard of care will be considered as a control

Eligibility

Sex: MALEMin age: 2 YearsMax age: 10 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Children undergoing elective Hypospadias repair * with American Society of Anesthesiologists (ASA) physical status I * age 2-10 years Exclusion Criteria: * Coagulation disorder * allergy to study medications * major malformations of the lower spine or meninges or any cutaneous or subcutaneous lesion at the site of injection.

Locations (1)

Assiut University Hospital

Asyut, Egypt

Outcomes

Primary Outcomes

Postoperative pain intensity Measured by Face, Legs, Activity, Cry & consolability (FLACC) pain scale

Time frame: During 24 h in the postoperative period

Secondary Outcomes

Cortisol level

Time frame: 6 hours

Data from ClinicalTrials.gov

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