This study evaluate the rate of nausea and nutritional status in patients with hyperemesis gravidarum (severe nausea and vomiting in pregnancy) and healthy pregnant women using a questionnaire (PUQE-score), self-reported food/drink intake form and blood test. The Investigators aim for developing normal range of prealbumin measurements (reference values) during first trimester of pregnancy.
Women affected with hyperemesis gravidarum are at severe nutritional risk. Reference values for biochemical parameters evaluating nutritional status during early pregnancy needs to be determined. The investigators will compare clinical nutritional parameters (weight gain/weight loss) with rate of nausea (PUQE-questionnaire), self-reported nutritional intake form and biochemical measurements (prealbumin) in women admitted to hospital with hyperemesis gravidarum and healthy pregnant women. For hyperemesis patients measurements will be repeated at discharge.
Study Type
OBSERVATIONAL
Enrollment
60
PUQE-form encompassing last 24 hours completion
Food-list form encompassing last 24 hours completion
Measurement of biochemical nutrition marker(s); Prealbumin
Dpt. of Obstetrics and Gynaecology, Haukeland University Hospital
Bergen, Hordaland, Norway
RECRUITINGPrealbumin in normal pregnancy
Serum Prealbumin measured during first trimester of pregnancy
Time frame: Within 24h at inclusion
Prealbumin related to nutritional parameters
Prealbumin level correlated to PUQE-score and weight change in normal and hyperemesis pregnancies
Time frame: Within 24h at inclusion
Change in Prealbumin
Change in Serum Prealbumin during hospital treatment of hyperemesis gravidarum
Time frame: Patients will be followed until discharge from hospital, a mean of 5 days, and blood sampling repeated at discharge
Prealbumin in Hyperemesis gravidarum
Serum Prealbumin measured when admission to hospital
Time frame: Within 2h from admission to hospital
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PUQE-form, nutritional form and Blood sampling