The researchers hope to learn if yoga complementary therapy would improve health-related quality of life, recovery of urinary continence and erectile function in patients who underwent prostate cancer surgery (i.e. radical prostatectomy). We hypothesized that in patients undergoing radical prostatectomy, preoperative and postoperative Yoga complementary therapy would improve health- related quality of life (HRQOL), recovery of urinary continence and erectile function. This two-arm, randomized controlled pilot study will compare Yoga intervention to usual care group. The aim is to evaluate the efficacy of Yoga complementary therapy on HRQOL in patients who underwent radical prostatectomy (RP). Yoga therapy will be given to the intervention group three times in a week for 6 weeks prior to surgery and then initiated 3 weeks after the surgery for another 6 weeks. The yoga exercise will be tailored to the participant's comfort level. As an exploratory analysis, we will evaluate pro-inflammatory and immunological markers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
30
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States
Change from baseline in health related quality of life measures
health related quality of life measures including but not limited to fatigue level, recovery urinary continence, and erectile function.
Time frame: One year
Change from baseline in 6-minute walk test
Time frame: One year
Total number of participants recruited to and withdraw from the study
Time frame: One year
Total number of participants completed the study
Time frame: One year
Number of Participants With Treatment-Related Adverse Events as Assessed by CTCAE v4.0
Time frame: One year
Change from baseline level on pro-inflammatory biomarkers
Time frame: one year
Change from baseline level on cellular immune response (i.e. measuring the Natural Killer Cell and regulatory-T cells)
Time frame: One year
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