36 patients with interstitial lung disease will be randomized to 1 weeks treatment with morphine hydrochloride as oral linctus 5 mg, four times a day, and 5 mg as needed up to 4 times a day, or corresponding doses of placebo. VAS score for dyspnea will be evaluated after 1 hour and 1 week at follow up. Other questionnaires will also be evaluated (GAD-7, K-BUILD, Leicester score)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
36
Aarhus University Hospital
Aarhus C, Denmark
VAS dyspnea score
Time frame: 1 week
Oxygen saturation
Peripheral oxygen saturation will be measured after first dose of morphine and placebo as well as after 1 week follow up
Time frame: 1 hour and 1 week
K-bild questionnaire
questionnaire regarding interstitial lung specific life quality
Time frame: 1 week
GAD-7 questionnaire
VAlidatet score for anxiety and depression
Time frame: 1 week
6 min walk test
Time frame: 1 hour and 1 week
Leicester Score
cough related score
Time frame: 1 week
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