A Study of Sunitinib in Patients With Metastatic or Recurrent Thymic Carcinoma

Inclusion Criteria: 1. Provision of signed, written and dated informed consent prior to any study specific procedures 2. Histopathologically confirmed metastatic or recurrent thymic thymic carcinoma 3. Age ≥ 20 4. ECOG PS 0-2 5. Documented progressive disease after one or more conventional systemic chemotherapy 6. At least one measurable disease by RECIST v1.1 7. Adequate organ function for treatment as follows: * Absolute neutrophil count \> 1.5 x 109/L * Platelets \>100 x 109/L * Serum creatinine ≤ 2.0 x ULN (upper limit of normal) * Serum bilirubin ≤ 1.5 x ULN * AST and ALT ≤ 2.5 x ULN (without liver metastasis), ≤ 5.0 x ULN (with liver metastasis) 8. Life expectancy ≥ 12 weeks at day 1 Exclusion Criteria: 1. Previous treatment with sunitinib or other VEGF-TKIs 2. Any major operation or irradiation within 4 weeks of baseline disease assessment 3. Any clinically significant gastrointestinal abnormalities which may impair intake or absorption of the study drug 4. CNS metastasis with continuous corticosteroid use within 4 weeks of baseline disease assessment (Asymptomatic CNS metastasis patients can be enrolled) 5. Patients with uncontrolled or significant cardiovascular disease (AMI within 12 months, Unstable angina within 6 months, NYHA Class III, IV Congestive heart failure or left ventricular ejection fraction below local institutional lower limit of normal or below 45%, Congenital long QT syndrome, Any significant ventricular arrhythmia, Any uncontrolled second or third degree heart block, Uncontrolled hypertension) 6. Concomitant malignancy (except adequately treated basal cell cancer of skin or cervical cancer in situ) 7. Female patients who are pregnant, breast-feeding or male or female patients of reproductive potential who are not employing an effective method of birth control 8. Other severe acute or chronic medical condition or laboratory abnormality that may increase the risk associated with trial participation or investigational product administration or may interfere with the interpretation of trial results and, in the judgment of the investigator, would make the patient inappropriate for entry into this trial. (including active bleeding, untreated DVT or thromboembolism)