Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 Allergen

Inclusion Criteria of TB (tuberculosis:include pulmonary tuberculosis and extra pulmonary tuberculosis) subjects: * judge the pulmonary tuberculosis patient according to Health industry standard of the People's Republic of China WS288-2008:Diagnostic Criteria for pulmonary tuberculosis; * 18 to 65 years old ,no gender limited; * Consent and signed informed consent forms (ICF); * Comply with follow-up. Inclusion Criteria of extra pulmonary tuberculosis subjects: * Diagnosed extra pulmonary tuberculosis by epidemiology, imaging, clinical symptoms, pathological examination and so on; * Lesions outside the lungs; * be in unfinished reinforced phase by chemotherapy; Exclusion Criteria of TB (tuberculosis) subjects: * Accompanied by the following severe illness:advanced cancer, diabetes, copd in acute episodes, acute/progressive liver disease or kidney disease, congestive heart failure, ect; * Taking part in other clinical or within three months involved in any other clinical; * Severe allergic constitution:allergic to two or more drugs; * in pregnancy or lactation; * in a mental illness; * Any conditions affect the trial evaluation by investigator's judgement. Inclusion Criteria of non-TB participants with lung disease: * A clear lung disease but can exclude pulmonary tuberculosis by clinical symptoms, imaging, laboratory examination. * 18 to 65 years old, no gender limited; * Consent and signed informed consent forms (ICF); * Comply with follow-up. Exclusion Criteria of non-TB participants with lung disease: * Accompanied by the following severe illness: advanced cancer, diabetes, copd in acute episodes, acute/progressive liver disease or kidney disease, congestive heart failure, ect; * Taking part in other clinical or within three months involved in any other clinical; * Severe allergic constitution: allergic to two or more drugs; * in pregnancy or lactation; * in a mental illness; * history of tuberculosis; * Any conditions affect the trial evaluation by investigator's judgement. Inclusion Criteria of suspected TB participants with lung disease: * Cases who have pulmonary tuberculosis by clinical symptoms/signs:appear cough、cough with hemoptysis、pectoralgia、dyspnea、fever（low-grade fever at afternoon）,together with night sweats、weak、loss of appetite、weight loss,and so on,or other easily-confused respiratory system disease with TB; * 18 to 65 years old, no gender limited; * Consent and signed informed consent forms (ICF); * Comply with follow-up. Exclusion Criteria of suspected TB participants with lung disease: * Accompanied by the following severe illness: advanced cancer, diabetes, copd in acute episodes, acute/progressive liver disease or kidney disease, congestive heart failure, ect; * Taking part in other clinical or within three months involved in any other clinical; * Severe allergic constitution: allergic to two or more drugs; * in pregnancy or lactation; * in a mental illness; * history of tuberculosis; * Any conditions affect the trial evaluation by investigator's judgement.