Study to Assess PK/PD Character, Safety/Tolerability of CKD-519 New Formulation in Healthy Male Subject.

Inclusion Criteria: 1. Between 20 aged and 45 aged in healthy male adult 2. Body weight ≥ 50kg and in the range of calculated BMI(Body Mass Index) 18\~29kg/m2 3. Subject who sign on an informed consent form willingly 4. Necessarily he agrees that use double contraceptions and do not sperm donation until two months during clinical trials and after the final dosage of investigational products Exclusion Criteria: 1. Clinically significant disease with cardiovascular, respiratory, hepatobiliary, nephrological, hematological, gastrointestinal, endocrine, immune, integumentary, neurologic, psychiatric system 2. Have a acute disease within 28 days before the beginning of study treatment 3. Have a disease history that can effect drug absorption, distribution, metabolism, excretion 4. Have a clinically significant chronic disease 5. Systolic blood pressure \<100mmHg or \>140mmHg, diastolic blood pressure\<60mmHg or \>90mmHg 6. Positive for serology test (HBsAg, anti-HCV Ab, anti-HIV Ab, VDRL(Venereal Disease Research Laboratories)) 7. Subject treated ethical drug within 14 days before the beginning of study treatment 8. Subject treated over-the-counter or herbal medicine within 7 days before the beginning of study treatment 9. Have a clinically significant allergic disease (except for mild allergic rhinitis, allergic dermatitis with no drugs) 10. Cannot take standard Meal 11. Whole blood donation within 60 days prior to the first dosing or component blood donation within 20 days prior to the first dosing 12. Blood transfusion within 30 days 13. Taking drugs have received any other investigational drug within 90 days prior to the first dosing 14. Continuously taking caffeine(\>5 cups/day), drinking alcohol(\>30g/day), smoking excessive cigarettes(\>10cigarettes/day) 15. Impossible on who participants in clinical trial by investigator's decision including laboratory test result or another reasone(for example, noncompliance, a disobliging manner) 16. Subject treated metabolizing enzyme inducers or inhibitors including barbiturates within 30 days