With the aging of Chinese population, degenerative valvular disease is becoming more and more frequent, which has brought a heavy burden to our society. Taking aortic stenosis (AS) as an example, the incidence of AS in population over the age of 65 are about 2%, and in population above the age of 85 can be amounted to 4-8%, in the Western country. Since the invention of transcatheter aortic valve replacement (TAVR),aortic valve disease (AVD),including AS and aortic regurgitation (AR), has attracted more and more attention. To date, there are few data about the prevalence of AVD in China. The characteristics and prognosis of AVD in China are still unknown. Therefore, the investigators design a prospective, observational cohort study to investigate characteristics, treatments and prognosis of AVD in Chinese elderly population. The results of the study will provide a basis for the future national health policy for prevention and treatment of AVD in the elderly.
Study Type
OBSERVATIONAL
Enrollment
2,000
Cardiovascular (CV) death or hospitalization for heart failure (HF)
from date of enrollment until the date of first documented HF or date of death from any cause, whichever came first, up to 36 months
Time frame: 36 months
Surgical or transcatheter aortic valve replacement
from date of enrollment until the date of surgical or transcatheter aortic valve replacement, whichever came first, up to 36 months
Time frame: 36 months
Number of all-cause mortality
Time frame: from date of enrollment until the date of death for any-cause, up to 36 months
Number of patients developing major cardiovascular and cerebral events (MACCE)
Time frame: 36 moths
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