The Utility of Oxygen Insufflation During Flexible Fiberoptic Bronchoscope-guided Intubation

Yonsei University36 enrolled

Overview

This study investigate the utility of continuous oxygen insufflation during fiberoptic bronchoscope-guided intubation. One group receives oxygen via suction channel of fiberoptic bronchoscope during intubation. The other group does not receive oxygen during fiberoptic bronchoscope-guided intubation. Then, the velocity of deoxygenation difference of PaO2(baseline

Fiberoptic bronchoscope-guided intubation is a gold standard for intubation of a patient with anticipating difficult airway. This technique takes several minutes without oxygen supply, which results in hypoxia when it prolonged. If continuous supply of oxygen during procedure improve the oxygenation, we can reduce the risk of hypoxemia and increase the safety margin during procedure.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Lumbar Spinal Stenosis

Interventions

OxygenDRUG

Oxygen is supplied through suction port during bronchoscope-guided intubation.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients who have surgery under general oral endotracheal anesthesia with invasive arterial blood pressure monitoring Exclusion Criteria: * history of lung disease * abnormality in chest x-ray * anticipating difficult intubation * pregnant women * who is unable to understand and agree the consent form

Locations (1)

Gangnam severance hospital

Seoul, South Korea

Outcomes

Primary Outcomes

Velocity of PaO2 decrease

After administration of anesthetic agents and manual ventilation of 5 minutes, arterial blood sampling is collected. Then bronchoscope-guided intubation performed and arterial blood sample is collected immediately after the intubation completed. Time for intubation (between 1st and 2nd blood sample) is recorded. The difference of PaO2(before \& after intubation) is divided by the time taking for intubation.

Time frame: from mask removal to 1st manual ventilation after intubation, up to 5 minute

Secondary Outcomes

success of intubation

After 1st trial of intubation, the success of intubation is recorded. If it takes more than 300 sec, it will be considered failure.

Time frame: 300 sec after the beginning of intubation

PaO2

arterial blood samples are collected before and after intubation.

Time frame: 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute

PaCO2

arterial blood samples are collected before and after intubation.

Time frame: 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute

arterial blood samples are collected before and after intubation.

Time frame: 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute

visual field

Visual field is evaluated by the blinded observer. It is evaluated as followed;excellent, good, poor, impossible

Time frame: throughout the intubation with bronchoscope, upto 5 minute

Data from ClinicalTrials.gov

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