The purpose this study was to evaluate the therapeutic effect of a functional goat cheese on obese and overweight people with altered lipid profile. The functional goat cheese containing polyunsaturated fatty acid, in amounts exceeding other cheese, was developed to benefit cardiovascular health of people who need to normalize lipid profile; which in the long term can contribute to the prevention of cardiovascular diseases.
A randomized, parallel, double-blind, controlled is being performing to evaluate the effect of a functional goat cheese on lipid profile in overweight or obese volunteers who need a special diet. Were included 60 volunteers (men and women) aged between 18 and 65 years (IMC ≥27\<40 Kg/m2) with a cardiovascular risk (\<10%). The volunteers are being followed at La Paz University Hospital of Madrid. For 12 weeks, the volunteers should consume 60 g of cheese daily (functional cheese or control cheese) and to receive advice to follow a balanced and individualized hypocaloric diet as well as physical activity.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
60
60 g per day during 12 weeks
60 g per day during 12 weeks
La Paz University Hospital
Madrid, Madrid, Spain
change from baseline total cholesterol
Time frame: 0 and 12 weeks
change from baseline Low density lipoprotein cholesterol
Time frame: 0 and 12 weeks
change from baseline High density lipoprotein cholesterol
Time frame: 0 and 12 weeks
change from baseline Triglycerides
Time frame: 0 and 12 weeks
change from baseline Apolipoprotein A1
Time frame: 0 and 12 weeks
change from baseline Apolipoprotein B
Time frame: 0 and 12 weeks
change from baseline Free fatty acids (FFA) in the plasma
Time frame: 0 and 12 weeks
change from baseline Erythrocyte membrane fatty acid composition
Time frame: 0 and 12 weeks
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