Obstructive sleep apnea (OSA) is a prevalent disorders characterized by intermittent obstructions of the upper airway during sleep. Continuous Positive Airway Pressure (CPAP) has been shown to be the most efficacious treatment for OSA. It consists of a small device that provides positive airway pressure delivered by a mask attached to the patients nose/mouth.
The primary purpose of this study is to evaluate the multinight (MNT) algorithm on patients with Obstructive Sleep Apnea (OSA) over 45 nights while using a CPAP machine at home. The researchers are evaluating the performance of the existing algorithm as well as capturing the data to make enhancements. Two main stages of this algorithm will be assessed: i. Fast Track (FT) stage. In the FT stage the aim is to assess if the algorithm reliably and timely reaches approximate therapeutic pressure levels. ii. Slow Titration (ST). In the Slow Titration stage the aim is to assess if data samples have been appropriately collected in a pressure range so that the therapeutic pressure can be inferred according to the algorithm proposed.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
1
The multinight (MNT) algorithm will be evaluated on patients with Obstructive Sleep Apnea (OSA) over multiple nights while using CPAP in the home for a total of 45 days. In particular the main goal is to assess the behavior of the two main stages of the algorithm: 1. Fast Track (FT) stage. Assesses if the algorithm reliably and timely reaches approximate therapeutic pressure levels. 2. Slow Titration (ST) stage.Assesses if data samples are appropriately collected in a pressure range so that the therapeutic pressure can be inferred according to the algorithm proposed. 1. Five days with standard auto titration. 2. MNT algorithm : 7 days (maximum) with Fast Track mode, 27 days (maximum) in Slow Titration mode. After PMNT is found, the device remains at PMNT for 5 sessions. Total approximately 45 days.
New York University School of Medicine
New York, New York, United States
Difference in number of residual events between high and low pressure levels
Residual events are represented by a given sleep disordered breathing index SDBIndex
Time frame: 45 days
Pressure level obtained during the MNT Fast Track stage
Time frame: 7 days
Number of days required to reach Fast Track pressure
Time frame: 7 days
Number of times the algorithm returns to Slow Track from the Fast Track stage
Time frame: 45 days
Variance in average obstruction of the upper airway during sleep measured by Obstruction Index (OI)
Time frame: 3 hours
Difference between pressure derived from multinight algorithm (PMNT) and Fast Track pressure
Time frame: 45 days
Difference between PMNT and sleep lab diagnosed CPAP pressure
Time frame: 45 days
Number of residual events while using the PMNT function
Time frame: 45 days
Average comfort rating using CPAP with multinight automated titration
Time frame: 45 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.