Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults

Inclusion Criteria: 1. Written or witnessed oral informed consent has been obtained. 2. Has Trichuris trichiura demonstrated in stool samples obtained during the week before enrolment: The presence of other helminths: Enterobius vermicularis, Ascaris lumbricoides, Necator americanus, Ancylostoma duodenalis will not be a cause for exclusion. 3. Is willing to comply with the requirements of the protocol and particularly to provide 4 stool samples, pretreatment and 7, 14 and 21 days after treatment. 4. Female patients of child bearing potential, who are using an established method of birth control (surgically sterile, intra-uterine contraceptive device, oral contraceptives, diaphragm in combination with contraceptive cream or foam, or condom in combination with contraceptive cream or foam) Exclusion Criteria: 1. The patient has demonstrated a previous hypersensitivity reaction to benzimidazole or other related compound. 2. Presence of other helminths without Trichuris trichiura. Note: Non-target species may be present and details of response will be recorded. 3. The patient has diarrhoeal disease that would interfere with the evaluation of stool samples. 4. The patient has received an anthelminthic in the 2 weeks prior to enrolment into the study. 5. The patient has received an investigational drug within 30 days or 5 half-lives (whichever is longer) of the screening visit or is scheduled to receive such a drug during the study period. 6. The patient has a concomitant infection or any other underlying disease that would compromise the diagnosis and the evaluation of the response to the study medication. 7. The patient has a known history of renal dysfunction (plasma creatinine ≥ 1.5 times upper limit of normal for age) or hepatic dysfunction (liver enzymes ≥ 1.5 8. Is a female who is pregnant, lactating or planning a pregnancy during the study, or is not practicing any form of contraception (see inclusion criteria (4.2.5). 9. Patient that is unwilling or unable to take part in this study. 10. The patient has previously been enrolled in the study.