The investigators are investigating whether slow administration of carbetocin is tolerated by patients better than if it is administered quickly, with respect to side effects such as headache, nausea, vomiting and facial flushing.
Patients undergoing elective cesarean under spinal are included in the study. These patients are treated with carbetocin to reduce blood loss from the lining of the womb after delivery of the baby. The study is a randomised double blind controlled trial with 2 groups. One group will receive carbetocin quickly, the second group will receive carbetocin slowly. The investigators will compare the difference between groups with respect to side effects and the effect of carbetocin on the cardiovascular system.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Enrollment
57
drug used to increase the tone of uterine muscle to prevent post partum hemorrhage after cesarean delivery.
BC Women's Hospital
Vancouver, British Columbia, Canada
percent change in cardiac output parameters as measured by non-invasive cardiac output monitor
the parameters will be presented as percentage change from the baseline, which is determined prior to the start of the study period
Time frame: 10 minutes
incidence of side effects occurring within timeframe below
headache, nausea, vomiting, facial flushing
Time frame: 30 minutes
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