The investigators are testing the hypothesis that administering 2L of body temperature warmed lactated ringer's intravenously prior to surgery can optimize the postoperative and recovery of patients undergoing total hip and total knee arthroplasty.
Hip and knee arthroplasty are safe and reliable surgeries for the majority of patients, but a small percentage experience major complications such as myocardial infarction, deep vein thrombosis (DVT), and pulmonary embolism (PE). As these complications are related to local tissue hypoxemia and patient immobility, interventions that can improve the ability of the heart to deliver blood to the tissue and help patients mobilize earlier in their postoperative course may decrease these complications. Based on recent evidence, it has been shown that many patients are dehydrated before surgery, which can make them feel nauseous, tired, and increase their perception of pain making them less likely to mobilize. This predisposes them to DVTs, pulmonary embolism, nausea and vomiting. Peri-operative dehydration can also decrease the ability of the lungs to oxygenate the blood properly and can place additional stress on the heart, which can increase the risk of heart attacks. The specific aim is to determine if patients' peri-operative hemodynamics can be improved with preoperative administration of 2 L of lactated ringers, and consequently reduce postoperative complications and improve recovery in arthroplasty patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
52
2L Lactated Ringer administered prior to primary knee or hip arthroplasty
No additional fluids will be administered
WVU Medicine Department of Orthopaedics
Morgantown, West Virginia, United States
Number of Participants With Postoperative Complications
Patients found to have a 90-day postoperative complication categorized as Infection, CHF/Fluid overload, MI, DVT/PE, other
Time frame: 90 days post surgery
90 Day Readmission Count
Patient readmitted to the hospital 90 day postoperatively
Time frame: 90 days postop
Duration of Hospital Stay (Hours)
Hours of Hospital Stay
Time frame: Surgery to hospital discharge
Duration of Surgery
Minutes recorded for length of surgery
Time frame: Incision to end of surgery
Emesis Episodes
Number of recorded emesis episodes in the medical record while patient was hospitalized
Time frame: Hospital Stay
Volume of Fluid Administred
milliliters of fluid administered during surgery
Time frame: surgical period
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