Assessment of Right Ventricular 2d-strain in Acute Respiratory Distress Syndrome

Central Hospital, Nancy, France49 enrolled

Overview

Assessment of right ventricular (RV) function in patients with acute respiratory syndrome (ARDS) is warranted because RV failure is frequent and associated with worse outcome. Transthoracic echocardiography is the cornerstone of RV assessment but it remains challenging. Quantification of RV deformation by speckle-tracking imaging echocardiography (STE) is a widely available and reproducible technique that readily provides an integrated analysis of all segments of the RV. This study aims to investigate the accuracy of STE-derived strain parameters in assessing RV function during ARDS.

Study Type

OBSERVATIONAL

Enrollment

Conditions

ARDS

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients with moderate or severe ARDS (Berlin definition) * receiving mechanical ventilation (\>48h estimated length) * Transthoracic echocardiography performed during the first 36h after ICU admission Exclusion Criteria: * pregnancy * protected or deprived of Liberty major * chronic respiratory disease * history of clinical right heart failure * chronic heart failure with LVEF \< 35% * severe valvular heart disease * under 18 or protected-adults

Locations (1)

Lemarie Jeremie

Nancy, France

Outcomes

Primary Outcomes

Measure of longitudinal peak systolic strain

Time frame: up to 36 hours after Intensive Care Unit admission

Secondary Outcomes

Measure of PaO2/FiO2 ratio

Time frame: up to 36 hours after Intensive Care Unit admission

Ventilator-free days

Time frame: 28 days

Mortality

Time frame: 28 days

Data from ClinicalTrials.gov

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