Management of Intracerebral Hemorrhage With Aminocaproic Acid - Pilot Study

Inclusion Criteria: 1. Age 18-80 years 2. Supratentorial ICH ≤ 30 mL in volume and seen on ≥ 2 slices on a 0.5 mm CT head 3. IVH involving \< 50% of the ipsilateral lateral ventricle will be allowed 4. Treatment initiated within 1 hour of baseline CT and 3 hours of onset or last known normal Exclusion Criteria: 1. Baseline mRS ≥ 2 2. Infratentorial hemorrhage (brainstem/cerebellum) 3. Any supratentorial hemorrhage extending to the brainstem 4. ICH \> 30 mL 5. Patients who undergo surgical evacuation 6. Presenting outside of the 3 hour window 7. Intraventricular extension \> 1/2 of one lateral ventricle 8. Intraventricular extension into the 3rd or 4th ventricle, or the aqueduct or involving \>50% of the ipsilateral lateral ventricle 9. ICH due to trauma 10. ICH due to aneurysm of arteriovenous malformation 11. ICH due to underlying neoplasm or infectious mass 12. ICH due to Warfarin or other oral or intravenous anticoagulants 13. International normalization ratio \> 1.4 14. Life expectancy \< 1 year (prior to ICH onset); due to any cause. 15. History of recent ischemic stroke (within the past 3 months) 16. History of deep vein thrombosis or pulmonary embolism 17. History of recent myocardial infarction (within the past 3 months) 18. Known history of hypercoagulable state 19. History of cancer 20. Glomerular filtration rate \< 60 mL/min 21. Received any hemostatic therapy for any indication (last 14 days) 22. Received any investigational therapy in last 90 days 23. "Do Not Resuscitate" order in place or expected, advance directives that could limit aggressive treatment measures.