Cluster headache (CH) is one of the most painful primitive headaches. Developments in neuroimaging have demonstrated activation of the ipsilateral hypothalamic and orexinergic system, which is similar in patients with addictions. CH has strong links to the vascular system but there is no study measuring endothelial function in CH sufferers.
Several studies have shown an association between Cluster headache (CH) and smoking. However, no data exists on the link between CH and other addictions, and impact of these addictions on clinical characteristics of the disease. In addition, despite the strong biological link between CH and the vascular system, systematic investigations about vascular functions in CH patients are lacking. This will be a prospective cohort study of 150 patients with CH, conducted in the Headache Center in Bordeaux, France.
Study Type
OBSERVATIONAL
Enrollment
95
Diagnostic and description of cluster headache
Scale and questionnaires
Psychopathological and cognitive questionnaires
CHU de Bordeaux
Bordeaux, France
Duration of active periods of cluster headache
Time frame: Day 0 (Inclusion visit)
Number of active periods
Time frame: Day 0 (Inclusion visit)
Duration of cluster headache
Time frame: Day 0 (Inclusion visit)
Severity of attacks
Time frame: Day 0 (Inclusion visit)
Duration of active periods of cluster headache
Time frame: one year after inclusion
Number of active periods
Time frame: one year after inclusion
Duration of cluster headache
Time frame: one year after inclusion
Severity of attacks
Time frame: one year after inclusion
Existence of an addiction
Time frame: Day 0 (Inclusion visit)
Existence of an addiction
Time frame: One year after inclusion
Severity of Addiction
Time frame: Day 0 (Inclusion visit)
Severity of Addiction
Time frame: One year after inclusion
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Blood sample for DNA collection
Endothelial function will be measured with a noninvasive Peripheral Arterial Tone (PAT) signal technology using the EndoPAT device
Reactive Hyperemic Index (RHI)
Endothelial function measurement
Time frame: Day 0 (Inclusion visit)