Predictive Factors of Endoscopic Mucosal Healing in Quiescent Ulcerative Colitis

Kyungpook National University Hospital127 enrolled

Overview

The purpose of this study is to determine whether fecal calprotectin, fecal immunochemical test, and Rome III criteria for irritable bowel syndrome (IBS) can predict mucosal healing in patients with quiescent ulcerative colitis (UC).

Study Type

OBSERVATIONAL

Enrollment

127

Conditions

Ulcerative Colitis

Interventions

colonoscopyOTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with ulcerative colitis who have no change of medication for at least 6 months * Patients with ulcerative colitis who are in remission (Mayo score \<3) * Patients with ulcerative colitis who will undergo colonoscopy for surveillance or mucosal healing check-up Exclusion Criteria: * Patients who refuse to participate * Patients who have a history of colectomy * Patients who have instinal stricture or perforation

Locations (1)

Keimyung University Dongsan Medical Center

Daegu, South Korea

Outcomes

Primary Outcomes

Mucosal healing

Endoscopic Mayo subscore \<1

Time frame: 1 week

Fecal calprotectin

Time frame: 1 week

Fecal immunochemical test

Time frame: 1 week

Secondary Outcomes

Rome III criteria for IBS

Time frame: 1 week

Data from ClinicalTrials.gov

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