The level of four biomarkers will be measured in the patients' plasma after induction of anaesthesia. There biomarkers are NT-ProBNP, ST2, Galectin-3 and GDF-15. The level of these marker will then be correlated with early (30 days) and late (one year) patients' prognosis and with functional recovery (MLHFQ score).
Study Type
OBSERVATIONAL
Enrollment
250
Aortic or mitral valve replacement/repair performed in isolation of in addition to coronary artery bypass graft(s).
CHU of Liege
Liège, Belgium
RECRUITINGComposite primary outcome
In hospital or 30-days mortality or inotropic support during more than 48 hours or lengthy of ICU stay longer than 5 days
Time frame: 30 days
ICU readmission
Time frame: 30 days
Post-operative AKI
AKIN stage during the first 48 hours
Time frame: 48 hours
Ejection fraction
EF at 30 days and at 1 year
Time frame: 1 year
NYHA
NYHA class at 30 days and at 1 year
Time frame: 1 year
MLHFQ
Minnesota living with heart failure questionnaire at 30 days and at 1 year
Time frame: 1 year
reshopitalisation
hospital admission for cardiac failure during the first postoperative year
Time frame: 1 year
one year mortality
mortality during the first postoperative year.
Time frame: 1 year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.