* Muscle cramps markedly affect the quality of life in cirrhotic patients with no highly effective drug. * Quinine was suggested for treatment of patients with muscle cramps in patients with liver cirrhosis. However, thrombocytopenia, cardiac arrhythmias and cinchonism are serious side effects.
• The aim of the study was to assess the efficacy and safety of Gabapentin in the treatment of muscle cramps in patients with liver cirrhosis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
Gapapentin twice daily
calcium carbonate twice daily
Tanta university - faculty of medicine
Tanta, Elgharbia, Egypt
Number of muscle cramps
Time frame: 3 months
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