A 2-year Longitudinal Study on the Structural and Optical Effects of Orthokeratology Treatment on Eye

The Hong Kong Polytechnic University99 enrolled

Overview

This is a two-year longitudinal study investigating the optical and structural effects of increased compression factor of orthokeratology lens on eyes and the corresponding effect on change in choroidal thickness and therefore myopic control.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Myopic Progression

Interventions

OrthokeratologyDEVICE

Eligibility

Sex: ALLMin age: 6 YearsMax age: 10 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 6 to 10 years old * Myopia: between 0.50 D and 4.00 D in both eyes * Astigmatism: \<1.50 D; ≤ 1.25 D for with-the-rule astigmatism (axes 180 ± 30); ≤ 0.50 D for astigmatism of other axes in both eyes * Anisometropia: ≤ 1.50 D * Symmetrical corneal topography with corneal toricity \<2.00 D in both eyes * Agree for randomization Exclusion Criteria: * Contraindications for orthokeratology wear (e.g. limbus-to-limbus corneal cylinder and dislocated corneal apex) * Any type of strabismus or amblyopia * Myopic treatment (e.g. refractive surgery and progressive lens wear for myopic control) before and during the study period * Rigid contact lenses (including orthokeratology lenses) experience * Systemic condition which might affect refractive development (for example, Down syndrome, Marfan's syndrome) * Ocular conditions which might affect the refractive error (for example, cataract, ptosis) * Poor compliance for lens wear or follow-up

Locations (1)

School of Optometry, The Hong KOng Polytechnic University

Hong Kong, China