Adipose Derived Stem Cells Transplantation for Chronic Obstructive Pulmonary Disease

Inclusion Criteria: * Age 40 to 80, inclusive * A prior diagnosis of moderate to severe COPD * GOLD IIa, III, IV Exclusion Criteria: * Pregnant or lactating * Life expectancy \< 6 months due to concomitant illnesses. * Exposure to any investigational drug or procedure within 1 month prior to study entry or enrolled in a concurrent study that may confound results of this study. * Any illness which, in the Investigators judgment, will interfere with the patient's ability to comply with the protocol, compromise patient safety, or interfere with the interpretation of study results * Subjects on chronic immunosuppressive or chemotherapeutic therapy * Known drug or alcohol dependence or any other factors which will interfere with the study conduct or interpretation of the results or who in the opinion of the investigator are not suitable to participate. * Subjects with Alpha-1 antitrypsin deficiency (an inherited disorder that can cause lung disease and liver disease). * Unwilling and/or not able to give written consent * Patient is positive for hepatitis (past history of Hepatitis A is allowed) * Any medical condition, which in the opinion of the clinical investigator, would interfere with the treatment or outcome of the patient * Cerebral aneurysm clips