The purpose of this study is to assess the risk of congenital cytomegalovirus (cCMV) infection in newborns born to seropositive women.
This study will be conducted at several Maternal and Child Health Hospitals (MCHHs) in China and the research activities will be integrated with routine medical services during pregnancy at the study sites.The investigators will build a perspective cohort study enrolling \~8000 pregnant women elder than 18 and following up their newborns at specific MCHHs.As a first step, The investigators will work with these hospitals to recruit the subjects. After being informed, the participants' remaining blood and urine samples (after their medical examinations) at their early, medium and late stages of pregnancy will be collected , and their newborns' urine and saliva samples will be collected after delivery. The aim of this study is to enroll 5000 series mother-newborns.
Study Type
OBSERVATIONAL
Enrollment
8,855
Maternity and Child care of Huli District
Xiamen, Fujian, China
Maternity and Child care of Xinmi City
Zhengzhou, Henan, China
Incidence of cCMV infection in newborns born to CMV seropositive pregnant women.
Time frame: up to 45 months
Incidence of cCMV infection in newborns to pregnant women with different maternal PP150-IgG titers in the early pregnancy.
Time frame: up to 45 months
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