Study of the Effect of Renal Impairment on the Pharmacokinetics of Vepoloxamer

Key Inclusion Criteria: * Subject must weigh ≤ 125 kg and have a body mass index between 20 and 40 kg/m2 * Subject must be willing to be confined in the clinical research unit for the duration of the study, up to 5 days * If female, subject must not be pregnant or lactating, have a negative pregnancy test, and agrees to sexual abstinence, or use of an appropriate birth control method from screening through 30 days after study drug administration * If male, subject agrees to sexual abstinence, is surgically sterile, or is using an appropriate birth control method from screening through 30 days after study drug administration * Considered by the Investigator to be healthy or clinically stable with respect to underlying renal impairment based on medical evaluation including vital signs, ECG and laboratory test results * Non-smoker, or smokes fewer than 10 cigarettes/day Key Exclusion Criteria * Uncontrolled medical condition (treated or untreated) considered to be clinically significant by the Investigator * Experienced an illness considered by the Investigator to be clinically significant within 2 weeks of study drug administration * Treatment with another investigational drug or device study within 30 days or 5 half-lives (whichever is longer) prior to screening * Positive test for drugs of abuse and/or positive alcohol test at Screening or Day -1 * Donated or lost a significant volume of blood or plasma within 90 days prior to study drug administration