Deep Brain Stimulation for Parkinson's Disease: the Globus Pallidus Internus Versus Subthalamic Nucleus

Inclusion Criteria: * Patients with a clinical diagnosis of idiopathic Parkinson's disease according to the international criteria that have not responded adequately to treatment with medication or who have complications related to prolonged use of L-dopa. * Patients who may be in the anesthetized or local or general anesthesia does not incur higher than expected risk in the general population. * Patients intellectually able to understand and sign the consent form. * Patients with hematological, metabolic and normal coagulation. Exclusion Criteria: * Age below 18 years * Impossibility to consent to participate in the study. * Patients during treatment with anti-coagulants or anti-platelet agents. * Patients with anatomical abnormalities that preclude access to the implantation of electrodes (eg cranial tumors or intracranial or cysts). * Patients with uncontrolled infection or other medical conditions pre-existing non-controlled (eg decompensated diabetes, hypertension, heart disease or symptomatic air). * History of primary or secondary myocardial ischemia, congestive heart failure, cardiac arrhythmia or bundle branch block refractory to treatment. * Concomitant treatment with other experimental drugs. * Pregnant or lactating.