Breast and colon cancer survivors with no evidence of disease, who score less than 45 in the PREDICT questionnaire for fatigue, will be randomized to a supervised strength program versus a supervised resistance program. The primary objective is improvement of cancer-related fatigue.
Patients should have finalized their oncological treatment in the previous 5 years. The sample size (32 patients) was calculated to improve the perception of fatigue score from an anticipated initial 38 to a post-intervention 48. The control arm consist of supervised strength training in two sessions per week with non-supervised international recommendations for aerobic exercise. The experimental arm will consist of supervised strength + resistance training in two sessions per week. After evaluating the weekly physical activity through accelerometer, body composition through DEXA and the cardiorespiratory fitness through CPET, participants will initiate the training according to a randomized assignment. Secondary objectives include: 1. cardiorespiratory fitness, 2. quality of life; 3. adherence to the training program; 4. adherence to international recommendations, 5. body composition, 6. employment status
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
32
Supervised vigorous aerobic training
Hospital Universitario Puerta de Hierro-Majadahonda
Majadahonda, Madrid, Spain
Improvement in cancer related-fatigue
Time frame: 4 months
Changes in cardiorespiratory fitness
measured through CPET
Time frame: 4 months
Changes in quality of life
measured through EORTC QLQ C30
Time frame: 4 months
adherence to the program
Time frame: 4 months
adherence to international recommendations
measured by accelerometer
Time frame: 4 months
Changes in body composition
measured by DEXA (Dual Energy X-Ray Absortiometry)
Time frame: 4 months
Employment status
Time frame: 4 months
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