The Clinical Characteristics of the Patients With Choledocholithiasis Without Cholangitis

Gangnam Severance Hospital44 enrolled

Overview

Laboratory change induced by common bile duct (CBD) stone is in general observed as the higher elevation of alkaline phosphatase (ALP) and gamma-glutamyl transpeptideas (ɤ-GT), in comparison to those of aspartate aminotransferase (AST) and alanine aminotransferase (ALT). However, some patients with CBD stone show the marked increased level of aminotransferase, which sometimes leads to misdiagnose those as liver disease caused by viral hepatitis, ischemia, and drug toxicity. The aim of this study is to investigate the clinicopathologic features of patients with CBD stones with the high level of aminotransferase in serum.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Choledocholithiasis

Eligibility

Sex: ALLMin age: 20 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. patients were diagnosed with CBD stone under endoscopic retrograde cholangiopancreatography (ERCP) 2. patients showing above 400 IU/L of aminotransferase when at the first admitted into hospital and the control groups is the patients displaying normal AST and ALT. Exclusion Criteria: * 1\. underlying hepatobiliary disease 2. alcoholics 3. cholangitis

Outcomes

Primary Outcomes

clinicopathologic features of patients with CBD stones with the high level of aminotransferase

lab finding, radiologic images, and findings under ERCP such as CBD diameter, CBD stone diameter, CBD stone number, periampullary diverticulum.