Change In Diaphragmatic Thickness Predicts Extubation Success

Albert Einstein Healthcare Network57 enrolled

Overview

We will investigate whether measurement of the change in thickness of the diaphragm during the respiratory cycle by ultrasound can predict extubation success in a 48 hour window. We will also asses whether this is only possible on low levels of pressure support as has been shown previously, or if this technique retains its predictive power at higher levels of pressure support.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Mechanical Ventilation Complication

Interventions

Diaphragm UltrasoundPROCEDURE

Once on a pressure support weaning trial, enrolled subjects will have an ultrasound of their right hemidiaphragm performed on three levels of pressure support: 15/5 10/5 and 5/5

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age greater than 18, ventilated for \>24 hours Exclusion Criteria: * already chronically on mechanical ventilatory support, already has tracheostomy, has pathology that obscures visualization of the right hemidiaphragm, has acute stroke either hemorrhagic or ischemic, cannot identify appropriate decision maker to get informed consent.

Locations (1)

Einstein Medical Center

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Extubation Success

Discontinuation from mechanical ventilation in 48 hours from ultrasound PI has left the institution. Efforts made to contact the PI were unsuccessful. No study data available.

Time frame: 48 hours

Secondary Outcomes

Re-intubation

Reinstitution of mechanical ventilation within 48 hours of extubation PI has left the institution. Efforts made to contact the PI were unsuccessful. No study data available.

Time frame: 48 hours from removal of ventilatory support

Data from ClinicalTrials.gov

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