Counteracting Learned Non-use Through Augmented Visuomotor Feedback in Virtual Reality (RGS)

Universitat Pompeu Fabra23 enrolled

Overview

The purpose of this study is to determine if Reinforcement-Induced Movement Therapy (RIMT), a novel rehabilitation method that augments visuomotor feedback of movements of the patient in virtual reality, is effective in treating hemiparesis resp. learned non-use.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Hemiparesis

Interventions

Reinforcement-Induced Movement Therapy (RIMT)BEHAVIORAL

6 weeks, 1 session a day, 30min per sessions, of physical therapy using a VR rehabilitation gaming system (RGS) with augmented visuomotor feedback

VR-based motor rehabilitation in RGS without augmented feedbackBEHAVIORAL

6 weeks, 1 session a day, 30min per sessions, of physical therapy using a VR rehabilitation gaming system (RGS)

Eligibility

Sex: ALLMin age: 25 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Mild-to-moderate upper-limbs hemiparesis (Proximal Medical Research Council Scale \> 2) due to ischemic or hemorrhagic stroke * Spasticity in the affected limb (Modified Ashworth Scale \<3) * First-ever ischemic or hemorrhagic stroke (\>4 weeks post-stroke) * Sufficient cognitive capacity for following the instruction of the intervention (Mini-Mental State Evaluation \>24) Exclusion Criteria: * Cognitive impairment that impede the correct execution or understanding of the intervention * Severe impairments in vision or visual perception abilities (such as vision loss or spatial neglect), in spasticity, in communication abilities (such as aphasia or apraxia), severe pain as well as other neuromuscular or orthopedic changes that impede the correct execution of the intervention training * Mental dysfunctioning during the acute or subacute phase after the stroke.

Outcomes

Primary Outcomes

The upper extremity Fugl-Meyer Assessment

change from baseline in motor function

Time frame: at baseline, at 6-weeks (after intervention), and at 12-weeks follow-up

Secondary Outcomes

Chedoke Arm Hand Inventory

change from baseline in functional recovery

Time frame: at baseline, at 6-weeks (after intervention), and at 12-weeks follow-up

Barthel Index

change from baseline in activities of daily living

Time frame: at baseline, at 6-weeks (after intervention), and at 12-weeks follow-up

Hamilton Scale

change from baseline in measurement of depression

Time frame: at baseline, at 6-weeks (after intervention), and at 12-weeks follow-up

Data from ClinicalTrials.gov

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