Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control

University of Toronto60 enrolled

Overview

The investigators hypothesized that consuming crackers or pasta enriched with faba bean fractions (faba bean protein concentrate, faba bean protein isolate, faba bean flour and faba bean starch), would reduce the blood glucose response to the meal compared to foods without faba bean components and reduce food intake at a meal

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Obesity Diabetes

Interventions

Crackers/pasta with added faba bean protein concentrateDIETARY_SUPPLEMENT

Protein concentrate treatment

Crackers/pasta with added faba bean protein isolateDIETARY_SUPPLEMENT

Protein isolate treatment

Crackers/pasta with added faba bean starchDIETARY_SUPPLEMENT

Starch treatment

Eligibility

Sex: MALEMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Non-smoking * No metabolic disease * BMI 20 - 25 kg/m\^2 * Male * Age 18-30 Exclusion Criteria: * Intolerance to treatments * Currently taking appetite-modifying medications * Restrictive eating * Smoking * Over- or underweight * Breakfast-skipping

Locations (1)

University of Toronto

Toronto, Ontario, Canada

Outcomes

Primary Outcomes

Change in blood glucose levels

Each participant will attend 5 sessions in total (randomized 5-arm cross-over design)

Time frame: Starting at the beginning of each session (0 minutes, before consumption of treatment) and every 15 - 30 minutes up to 200 minutes (time of completion of each session)

Change in gut hormone levels measured in the blood

Each participant will attend 5 sessions in total (randomized 5-arm cross-over design)

Time frame: Starting at the beginning of each session (0 minutes, before consumption of treatment) and every 30 minutes up to 200 minutes (time of completion of each session)

Secondary Outcomes

Subjective appetite

Measured using Visual Analog Scales (VAS)

Time frame: From 0 to 200 minutes

Ad libitum food (pizza meal) intake as measured by the amount of pizza (in grams) consumed during the 20 minute period

Each participant will also answer questions related to physical comfort, motivation to eat, and rating feelings of energy and fatigue using Visual Analog Scales (VAS)

Time frame: 120 minutes after completion of treatment, 20 minutes were allocated to allow for pizza consumption

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.