Quality of Life Changes on Lower Extremity Lymphedema Patients Using an Advanced Pneumatic Compression Device (PCD)

Inclusion Criteria: * Age 18 or older * Diagnosis of primary or secondary, unilateral or bilateral, lower extremity lymphedema * Ability and willingness to participate in all aspects of the study including following prescribed care * Ability to provide informed consent * Must have a prescription for the Flexitouch (Flexitouch system or Flexitouch Plus) Exclusion Criteria: * Diagnosis of active or recurrent cancer, or less than 3 months at the time of initial evaluation from the completion of chemotherapy, radiation therapy or primary surgery for the treatment of cancer. * Active skin or limb infection/inflammatory disease (acute cellulitis, or other uncontrolled skin or untreated inflammatory skin disease) * Acute thrombophlebitis (in last 2 months) * Pulmonary embolism within the previous 6 months * Deep Vein Thrombosis (DVT) within the previous 3 months * Severe peripheral artery disease (critical limb ischemia including ischemic rest pain, arterial wounds, or gangrene) * Pulmonary edema * Heart failure (acute pulmonary edema, decompensated acute heart failure) * Patients with poorly controlled asthma * Previous use of the study pneumatic compression device (PCD) * Currently using multi-layer bandaging (MLB) unless bandages can be removed for limb circumference measurements * Pregnant women or women of childbearing potential not on contraception * Any condition where increased venous and lymphatic return is undesirable * Currently participating in another medical device or drug clinical trial * Signs of noncompliance at the week 4 visit including: using the device less than 3 times per week and/or not attending the scheduled visit.