To evaluate the diagnostic accuracy of the 18Fluor-fluorodeoxyglucose (\[18F\]FDG) in the Positron Emission Tomography/Computed Tomography (PET/CT) as compared to mediastinoscopy for staging of non-small cel lung carcinoma.
The main aim of this study is to validate the \[18F\]FDG on PET/CT for the diagnosis of metastatic ganglions at the mediastinum in SUS patients with non-small cell lung carcinoma considering sensitivity, specificity, positive predictive value, negative predictive value, accuracy. Other specific aims are: * Analyze the diagnosis performance of the \[18F\]FDG on PET/CT in two timepoints (1 and 2 hours after exam), in relation to the staging of the non-small cell lung carcinoma * Evaluate the addition of the iodinated contrast in the \[18F\]FDG to improve the images obtained from the PET/CT in the staging of the non-small cell lung carcinoma
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
108
Instituto do Cérebro do Rio Grande do Sul
Porto Alegre, Rio Grande do Sul, Brazil
Validate the [18F]FDG as an alternative method for non-small lung carcinoma diagnosis
Time frame: 4 years
Number of patients diagnosed in a positive manner with the gold standard and with the alternative method
Time frame: up to 30 days following recruitment
Number of patients with a negative diagnosis according to the gold standard and the alternative method
Time frame: up to 30 days following recruitment
Number of true positives among positive diagnosed patients with the alternative method
Time frame: up to 30 days following recruitment
Number of false positives among patients negatively diagnosed with the alternative method
Time frame: up to 30 days following recruitment
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