The purpose of this study is to assess the safety and efficacy of Tavilermide Ophthalmic Solution compared with Placebo Ophthalmic Solution in treating the signs and symptoms of dry eye disease.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
400
1% Tavilermide BID Dosing
Vehicle Ophthalmic Solution
MIM-726 Investigational Site
Torrance, California, United States
Total Corneal Fluorescein Staining Using The Ora Calibra Scale
An assessment of the total corneal fluorescein staining using the Ora Calibra Scale both immediately prior to and immediately following exposure to a challenge in a controlled adverse environment (CAE)
Time frame: Day 57
Ocular Discomfort Using The Ora Calibra Scale
A patient-reported subjective assessment of ocular discomfort recorded at each of the 5 office visits throughout the treatment period
Time frame: Day 57
Total Corneal Fluorescein Staining Using The Ora Calibra Scale
An assessment of the total corneal fluorescein staining using the Ora Calibra Scale both immediately prior to and immediately following exposure to a challenge in a controlled adverse environment (CAE)
Time frame: Day 15
Ocular Surface Disease Index
Time frame: Day 57
Ocular Dryness Using The Ora Calibra Scale
A patient-reported subjective assessment of ocular dryness recorded twice daily over the complete treatment period.
Time frame: 8 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.