Pre-eclampsia and Biochemical Markers

Assiut University90 enrolled

Overview

In view of both endothelial injury in pre-eclampsia, high blood pressure and kidney impairment characteristics, a recent study demonstrated that the serum levels of NGAL increased at the end of the second trimester in women who subsequently developed pre-eclampsia compared to the control group. This correlates well with the endothelial damage that occurs during pre-eclampsia and thus NGAL can be considered as a promising marker in predicting both early and late onset pre-eclampsia. It may be required to combine one or more biomarker with NGAL to increase the precision, and sensitivity for detection of risk and reliability of using biomarkers for pre-eclampsia.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Detection of Preeclampsia Complications

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 20-40 years. * Gestational age \>20 weeks. Exclusion Criteria: * Patients with preexisting renal disease,hypertension, diabetes mellitus, gestational hypertension. * Patients Refuse to participate in the study * Patients already have complicated preeclampsia.

Locations (1)

Ahmed Abbas

Assiut, Cairo Governorate, Egypt

Outcomes

Primary Outcomes

The level of circulating NGAL

Time frame: 24 hours

Data from ClinicalTrials.gov

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