The current trial is evaluating the integration of a pretherapeutical FDG-PET/MRI in the adjuvant radiochemotherapy in patients with head and neck cancer. As a secondary hypothesis the intention is to develop of a multi-parametric decision support system for personalised medicine by integrating functional imaging, γH2AX-analysis and genetic information.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
49
Integration of pretherapeutical PET/MRI in adjuvant radiotherapy
University Hospital Tübingen, Department of Radiation Oncology
Tübingen, Baden-Wurttemberg, Germany
locoregional progression free survival
15% improvement in loco-regional PFS at 2 years through integrtion of pre-operative PET/MR imaging into RT treatment planning
Time frame: 2 years after primary diagnosis
Disease free survival
Time frame: 2 years after primary diagnosis
Overall survival
Time frame: 2 years after primary diagnosis
Development of a multi-parametric decision support system
Time frame: after termination of recruitment and follow up up to 5 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.