Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%

Inclusion Criteria: * Female subjects aged ≥ 42 years and ≤ 65 years, in post-menopausal period for at least 1 year and with active sexual life; * Serum testosterone levels \< 33 ng/mL; * Follicle-stimulating hormone (FSH) levels \> 22 mU/mL; * Absence of other significant diseases which, at the physician's discretion, could impact subject's participation in the trial, according to protocol requirements, and study evaluations: medical history, blood pressure and heart rate measurements, physical examination and complimentary laboratory tests; * Ability to understand the nature and objective of the trial, including risks and adverse events, which shall be confirmed by Informed Consent Form signature. Exclusion Criteria: * Screening laboratory tests results presenting clinically relevant deviations that, at the investigator discretion, prevent the subject to participate in the trial due to possible risks; * Drugs addiction, including alcohol; * Treatment with any drugs known to have a well-established toxic potential to major organs, within 3 months before the trial, ; * Participation in any other experimental research or administration of any experimental drug within six months before the initiation of this trial; * Pregnancy, labor or miscarriage in the last 12 weeks before the antecipated date of the study treatment start; * Any conditions, according to investigator's best judgement, that prevents the subject to participate in the trial.