The purpose of the study is to test the clinical efficacy of oral Vitamin D3 on Wound Healing in patients with Chronic Rhinosinusitis With Nasal Polyposis and Lower Vitamin D Levels After Endonasal Endoscopic Sinus Surgery
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
The First Hospital of Shanxi Medical University
Taiyuan, Shanxi, China
RECRUITINGVAS evaluation of usual symptoms in patients with CRSwNP
The evaluated symptoms were nasal obstruction, anterior nasal discharge and post-nasal drip, smelling reduction and facial pain
Time frame: at 8 weeks after first drug intake
Questionnaire:SNOT-20 evaluates the quality of Life
Time frame: at 8 weeks after first drug intake
Change of Lund-Kennedy scores
Time frame: at 8 weeks after first drug intake
Inflammatory mediators in serum
Time frame: 8 weeks
Histologic analysis of nasal mucosa
Time frame: 8 weeks
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