Misoprostol for Second Trimester Pregnancy Termination

Assiut University180 enrolled

Overview

The majority of second-trimester pregnancy termination performed in the United States are performed surgically by dilation and evacuation. The frequency of induction of abortion increases as gestational age advances. In the late second trimester and early third trimester, induction is the primary method of termination in cases of fetal abnormalities. In many other countries, however, induction is the primary method of abortion throughout the second trimester

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

180

Conditions

Intra Uterine Fetal Death

Interventions

termination of second trimester pregnancyPROCEDURE

Intra uterine extra amniotic (200 μg ) versus Vaginal (200 μg) Misoprostol for Second Trimester Pregnancy Termination. Randomized controlled trial

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * Pregnancy 13-24 weeks. * Women with indication for termination of the pregnancy due to intra uterine fetal death Exclusion Criteria:-Pregnancy before 13 weeks. * Pregnancy beyond 24 weeks. * Women with scared uterus. * Known hypersensitivity for misoprostol. * Refusal of the woman to participate.

Outcomes

Primary Outcomes

mean duration from the initial misoprostol dose until complete fetal expulsion

Time frame: 24 hours

Data from ClinicalTrials.gov

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