The purpose of this multicenter study is to evaluate the ovarian reserve after alcohol sclerotherapy of endometriomas versus conventional surgery.
Between 5-10% fertile women are affected by endometriosis, and ovarian endometrioma is present in 17-44% of cases, with 40% of patients with endometriomas being sterile. However, the "gold standard" treatment is laparoscopic ovarian cystectomy and this therapy is associated with a diminished ovarian reserve, with a significant antimullerian hormone (AMH) decrease. Alcohol sclerotherapy is a new minimal invasive procedure in endometrioma treatment whose potential beneficial effect in fertility preservation is not still demonstrated. The investigators would like to demonstrate that this procedure improves fertility preservation and reduces morbidity and costs in contrast with conventional surgery. Moreover,the investigators would like to demonstrate that this procedure could be performed in different centers with similar results.
Study Type
OBSERVATIONAL
Enrollment
34
Laparoscopic surgery
US-guided sclerotherapy
Hospital Universitario Bellvitge
L'Hospitalet de Llobregat, Barcelona, Spain
AMH Test
the value of AMH after both procedures in ng/mL
Time frame: 6 months
antral follicles count
US antral follicles count after both procedures
Time frame: 6 months
tumoral markers: epididimal human protein 4 (HE-4) and CA125
the value tumoral markers after both procedures
Time frame: 6 months
complications
number of participants with complications
Time frame: 1 day
costs
costs (euros) of the procedures and their complications
Time frame: 1 day
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