An Exploratory Study of DS-8500a on Beta Cell Function Using Hyperglycemic Clamp

Inclusion Criteria: * Patients aged ≥ 20 years at the time of informed consent * Japanese patients with type 2 diabetes * Patients who have HbA1c ≥ 7.0% and \< 9.0% Exclusion Criteria: * Patients with type 1 diabetes mellitus or with a history of diabetic coma, precoma, or ketoacidosis * Patients receiving or requiring treatment with insulin * Patients with a body mass index (BMI) of \< 18.5 kg/m2 or ≥ 35.0 kg/m2 * Patients with clinically evident renal impairment (estimated glomerular filtration rate \[eGFR\] of \< 45 mL/min per 1.73 m2) or clinically significant renal disease * Patients with fasting plasma glucose ≥ 240 mg/dL