Effects of Soluble Fiber on Blood Pressure: A Meta-analysis of Randomly-controlled Trials

Unity Health Toronto500 enrolled

Overview

The present study conducted a meta-analysis of 22 randomly controlled trials to assess the effects of soluble fiber intake on blood pressure in human subjects. Using the Cochrane Handbook for Systematic Reviews of Intervention, a systematic review and meta-analysis was conducted. Information regarding study methods, characteristics, mean BP and standard deviations were extracted The data from each study were pooled using a random effects model to estimate the effects of soluble fiber consumption on blood pressure.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Blood Pressure

Interventions

Soluble FibreDIETARY_SUPPLEMENT

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Randomized Controlled Trials * Parallel or Crossover Design * Duration: \>3 weeks * Human trials * Viscous (soluble) fiber * Viable endpoint data * Articles published in English Exclusion Criteria: * Non-human * Non-randomized * Lack of control * Less than 4 weeks in duration * No viable endpoint data

Locations (1)

The Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre

Toronto, Ontario, Canada

Outcomes

Primary Outcomes

Systolic Blood Pressure

Time frame: 4 weeks

Diastolic Blood Pressure

Time frame: 4 weeks

Data from ClinicalTrials.gov

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