The discovery of antenatal bilateral renal anomaly poses an essential question: can we predict postnatal renal function? Ultrasound is insufficiently precise to predict postnatal renal function evolution. The objective of this study is to estimate the specificity and sensitivity of amniotic fluid biomarkers to predict postnatal renal function in fetuses with bilateral developmental nephropathies. Both fetuses with bilateral renal anomalies and control (healthy) fetuses will be included. For this study amniotic fluid will only be collected according to routine clinical practice and only excess amniotic fluid sample will be used for the study. The potentially identified biomarkers will not change routine management of the pregnancies in the study.
Study Type
OBSERVATIONAL
Enrollment
358
Hopital Nord
Amiens, France
Chu D Angers
Angers, France
Hopital Saint Jacques
Besançon, France
Hopital Pellegrin
Bordeaux, France
Hopital Morvan
Brest, France
Hopital Femme-Mere-Enfant
Bron, France
Ch Rene Dubos Pontoise
Cergy-Pontoise, France
Hopital Antoine Beclere (Ap Hp)
Clamart, France
Chu Estaing
Clermont-Ferrand, France
Hopital Du Bocage
Dijon, France
...and 21 more locations
Renal function (according to Schwartz formula)
Renal function (according to Schwartz formula)
Time frame: month 24
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