Association between serum anti-Mullerian hormone (AMH) level and prevalence of glucose intolerance and metabolic syndrome in women with polycystic ovary syndrome (PCOS)
* To study the association between serum anti-Mullerian hormone (AMH) level and glucose intolerance and metabolic syndrome in women with polycystic ovary syndrome (PCOS). * Glucose intolerance is detected by 2-hours 75 gram oral glucose tolerance test (OGTT). * Metabolic syndrome is diagnosed by using the Harmonized criteria; the presence of any 3 of 5 following risk factors constitutes a diagnosis of metabolic syndrome. 1. Elevated waist circumference (\> 80 cm in Asian women) 2. Elevated triglycerides (\> 150 mg/dL) 3. Reduced HDL-cholesterol (\< 50 mg/dL) 4. Elevated blood pressure )systolic \> 130 and/or diastolic \> 85 mmHg) 5. Elevated fasting glucose ( \> 100 mg/dL) * Percentage of glucose intolerance and metabolic syndrome in PCOS women as well was any differences in parameters between PCOS patients with and without glucose intolerance and metabolic syndrome will be analysed.
Study Type
OBSERVATIONAL
Enrollment
70
Serum for serum anti-Mullerian hormone, 2-hour 75 gram oral glucose tolerance test and lipid profiles
Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University
Bangkok, Bangkok, Thailand
RECRUITINGDifferences between serum AMH level between PCOS women with and without glucose intolerance and metabolic syndrome
Any differences between mean of serum AMH levels in PCOS with and without glucose intolerance and metabolic syndrome
Time frame: 6 months
Percentage of glucose intolerance in PCOS women
Percentage of glucose intolerance detected by 75 g OGTT in PCOS women
Time frame: 6 months
Percentage of metabolic syndrome in PCOS women
Percentage of metabolic syndrome defined by the Harmonized criteria in PCOS women
Time frame: 6 months
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