The purpose of this study is to Evaluation of absorption, metabolism, and excretion of \[14C\]-K-312 and estimation of the absolute bioavailability of K-312 in healthy male subjects
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
13
Single oral dose
microtracer dose containing ≤37 kBq (1000 nCi) \[14C\] given as a 5-ml IV push over 2 minutes
Unnamed facility
Madison, Wisconsin, United States
Area under the plasma-concentration time curve to last measured time point
Time frame: 336 hours post-dose
Oral bioavailability based on the ratio of AUC after oral dosing to the AUC after i.v. dosing
Time frame: 336 hours post-dose
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