The principal aim is to assess impact of alveolar recruitment manoeuvres (ARM) on stroke volume variation, evaluated by trans-oesophageal echocardiography (TEE). These variations will be measured on preload dependency or preload independency status. The principal purpose is to determine if variations of stroke volume during standardized ARM can predict the preload dependency status.
Population studied: anesthetized patients for cardiac surgery of coronary bypass. Secondary endpoints : - comparison between TEE and mini-invasive monitoring systems in accuracy of measurement of stroke volume variation during ARM. These mini-invasive systems are : Clearsight system (Edwards Lifescience) and Flotrac system (Edwards Lifescience) \- Difference between pre and post-cardiopulmonary bypass status on principal purpose evaluation
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
24
CHU Clermont-Ferrand
Clermont-Ferrand, France
Variation of stroke volume
Variation of stroke volume measured by TEE, induced by a standardized ARM, at the beginning of cardiac surgery
Time frame: at the beginning of cardiac surgery
Velocity time integral (cm)
Velocity time integral (cm) (TEE measurement)
Time frame: at the begining of cardiac surgery
Velocity time integral (cm)
Velocity time integral (cm) (TEE measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Velocity time integral (cm)
Velocity time integral (cm) (TEE measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Cardiac index (l/min/m2)
Cardiac index (l/min/m2) (TEE measurement)
Time frame: at the begining of cardiac surgery
Cardiac index (l/min/m2)
Cardiac index (l/min/m2) (TEE measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Cardiac index (l/min/m2)
Cardiac index (l/min/m2) (TEE measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Right ventricle diameter/left ventricle diameter ratio
Right ventricle diameter/left ventricle diameter ratio (TEE measurement),
Time frame: at the begining of cardiac surgery
Right ventricle diameter/left ventricle diameter ratio
Right ventricle diameter/left ventricle diameter ratio (TEE measurement),
Time frame: After fluid challenges until patient is on a preload independency state.
Right ventricle diameter/left ventricle diameter ratio
Right ventricle diameter/left ventricle diameter ratio (TEE measurement),
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
E/A ratio
E/A ratio (TEE measurement)
Time frame: at the begining of cardiac surgery
E/A ratio
E/A ratio (TEE measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
E/A ratio
E/A ratio (TEE measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Sus-hepatic vein Doppler profile
Sus-hepatic vein Doppler profile (TEE measurement)
Time frame: at the begining of cardiac surgery
Sus-hepatic vein Doppler profile
Sus-hepatic vein Doppler profile (TEE measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Sus-hepatic vein Doppler profile
Sus-hepatic vein Doppler profile (TEE measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Invasive arterial pressure (mmHg)
Time frame: at the begining of cardiac surgery
Invasive arterial pressure (mmHg)
Time frame: After fluid challenges until patient is on a preload independency state.
Invasive arterial pressure (mmHg)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Heart rate (pulse/min)
Time frame: at the begining of cardiac surgery
Heart rate (pulse/min)
Time frame: After fluid challenges until patient is on a preload independency state.
Heart rate (pulse/min)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Expired CO2 (mmHg)
Time frame: at the begining of cardiac surgery
Expired CO2 (mmHg)
Time frame: After fluid challenges until patient is on a preload independency state.
Expired CO2 (mmHg)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Central venous pressure (mmHg)
Time frame: at the begining of cardiac surgery
Central venous pressure (mmHg)
Time frame: After fluid challenges until patient is on a preload independency state.
Central venous pressure (mmHg)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Pulse pressure variation (%)
Time frame: at the begining of cardiac surgery
Pulse pressure variation (%)
Time frame: After fluid challenges until patient is on a preload independency state.
Pulse pressure variation (%)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Perfusion index (pulsoxymeter)
Time frame: at the begining of cardiac surgery
Perfusion index (pulsoxymeter)
Time frame: After fluid challenges until patient is on a preload independency state.
Perfusion index (pulsoxymeter)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Stroke volume (ml) (Flotrac measurement)
Time frame: at the begining of cardiac surgery
Stroke volume (ml) (Flotrac measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Stroke volume (ml) (Flotrac measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Stroke volume variation (%) (Flotrac measurement)
Time frame: at the begining of cardiac surgery
Stroke volume variation (%) (Flotrac measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Stroke volume variation (%) (Flotrac measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Cardiac index (l/min/m2) (Flotrac measurement)
Time frame: at the begining of cardiac surgery
Cardiac index (l/min/m2) (Flotrac measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Cardiac index (l/min/m2) (Flotrac measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Pulse pressure variation (%) (Flotrac measurement)
Time frame: at the begining of cardiac surgery
Pulse pressure variation (%) (Flotrac measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Pulse pressure variation (%) (Flotrac measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Arterial pressure (mmHg) (Flotrac measurement)
Time frame: at the begining of cardiac surgery
Arterial pressure (mmHg) (Flotrac measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Arterial pressure (mmHg) (Flotrac measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Stroke volume (ml) (Clearsight measurement)
Time frame: at the begining of cardiac surgery
Stroke volume (ml) (Clearsight measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Stroke volume (ml) (Clearsight measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Stroke volume variation (%) (Clearsight measurement)
Time frame: at the begining of cardiac surgery
Stroke volume variation (%) (Clearsight measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Stroke volume variation (%) (Clearsight measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Cardiac index (l/min/m2) (Clearsight measurement)
Time frame: at the begining of cardiac surgery
Cardiac index (l/min/m2) (Clearsight measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Cardiac index (l/min/m2) (Clearsight measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Pulse pressure variation (%) (Clearsight measurement)
Time frame: at the begining of cardiac surgery
Pulse pressure variation (%) (Clearsight measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Pulse pressure variation (%) (Clearsight measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Arterial pressure (mmHg) (Clearsight measurement)
Time frame: at the begining of cardiac surgery
Arterial pressure (mmHg) (Clearsight measurement)
Time frame: After fluid challenges until patient is on a preload independency state.
Arterial pressure (mmHg) (Clearsight measurement)
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
Near infrared spectroscopy : Cerebral SrO2
Time frame: at the begining of cardiac surgery
Near infrared spectroscopy : Cerebral SrO2
Time frame: After fluid challenges until patient is on a preload independency state.
Near infrared spectroscopy : Cerebral SrO2
Time frame: After the cardiopulmonary bypass period, when sternotomy will be closed
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.