Dilation and evacuation (D\&E) is a common surgical procedure in the U.S. Adequate pre-operative preparation of the uterine cervix is an important part of preventing complications of the procedure. Traditionally, the uterine cervix is prepared for the procedure using water-attracting dilators, which are placed via a speculum exam and cause discomfort for many women. The objective of this study is to investigate the comparative effectiveness of mifepristone (an oral tablet) versus dilators for cervical preparation for D\&E.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
400 mcg buccal 60-90 minutes prior to procedure
200 mg PO on the day prior to D\&E
osmotic cervical dilators inserted through the internal os
Planned Parenthood Mar Monte
San Jose, California, United States
Procedure Time
Measured as time from speculum insertion to removal.
Time frame: Intraoperative
Cervical Dilation
Measured by estimate with bimanual exam and passage of largest dilator immediately prior to procedure
Time frame: Baseline
Total Procedure Time
All time required by patient (time in clinic for cervical preparation procedures)
Time frame: Measured at clinic visit and on OR day, over 2 day period
Difficulty of Procedure, as reported by clinician
Using Visual Analogue Scale (VAS)
Time frame: Measured within 5 minutes after procedure
Complications/Adverse Events
Estimated blood loss, uterine injury, infection, retained products of conception
Time frame: Intraoperatively
Pain Perceived by Patient
Using Visual Analogue Scale (VAS)
Time frame: Intraoperatively "Measured during dilator placement"
Overall Patient Experience
Using Visual Analogue Scale (VAS)
Time frame: Measured post-operatively (30 minutes prior to discharge)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.