Lifestyle Intervention for Prevention of Gastric Neoplasm

Shandong University350 enrolled

Overview

The purpose of this study is to determine whether positive lifestyle interventions (diet modification and smoking cessation) are effective in the prevention of gastric pre-cancer and cancer occurrences and reccurence of gastric cancer after endoscopic resection.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

350

Conditions

Stomach Neoplasms

Interventions

Active measures of lifestyle modificationBEHAVIORAL

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis of chronic atrophy gastritis proved by gastroscopy biopsy pathology or early gastric cancer patients who have recieved endoscopic resection * have one or several bad lifestyle habits such as eating too much salt, eating too few fruits, smoking, drinking wine, and lack of sleep. Exclusion Criteria: * patients who refuse to change lifestyle according to the trial plan

Locations (1)

Linyi People's Hospital affiliated to Shandong University

Linyi, Shandong, China

Outcomes

Primary Outcomes

gastric caner occurrence

gastric cancer proved by gastroscopy biopsy

Time frame: 4 years

Secondary Outcomes

All cause mortality

Time frame: 5 years

gastric tissue DNA methylation change of selected genes

All patients have gastric biopsy through gastroscopy at the enrollment time and the last follow-up. DNA methylation status of selected genes are tested.

Time frame: 4 years

Data from ClinicalTrials.gov

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